Thou... Infectious Knotty-pated Barnacle
Parts of what makes up this insult can be found in "Henry IV" spoken by "PRINCE HENRY":

This insult has been seen 1 time on this site. This was on Thursday, October 26th, 2017gross as a mountain, open, palpable. Why, thou
clay-brained guts, thou knotty-pated fool, thou
whoreson, obscene, grease tallow-catch,--

A total of 10538 insults have been uniquely generated 11025 times, with a total of 125000 (or 50 to the third power) insults available in the system!